Search for retrovirus in the chronic fatigue syndrome.

نویسندگان

  • J W Gow
  • K Simpson
  • A Schliephake
  • W M Behan
  • L J Morrison
  • H Cavanagh
  • A Rethwilm
  • P O Behan
چکیده

AIM To examine peripheral blood and skeletal muscle from patients with chronic fatigue syndrome for exogenous retrovirus. METHODS Blood samples from 30 patients and muscle biopsy specimens of 15 patients were examined for retroviral sequences by DNA extraction, polymerase chain reaction (PCR), and Southern blotting hybridisation. Sera were examined for human foamy virus by western immunoblotting and indirect immunofluorescence techniques. RESULTS No differences between the patient and control populations was found for any of the PCR primer sets used (gag, pol, env, and tax regions of HTLV I/II). An endogenous gag band was observed in both the patient and control groups. All sera were negative for antibody to human foamy virus. CONCLUSION The results indicate that there is no evidence of retroviral involvement in the chronic fatigue syndrome.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

مقایسه کیفیت خواب و سندرم خستگی مزمن در کارکنان رادیولوژی با پرستاران شاغل در بیمارستان‌

Background and aims: sleep quality and fatigue are major aspects of human social life and can intrigue tension in healthcare workers, which ultimately causes dissatisfaction, quitting job and providing incorrect services to clients. This study aimed to determine the association between quality of sleep and chronic fatigue syndrome in nurses and radiology workers in hospital. Methods: This cr...

متن کامل

Chronic Fatigue Syndrome in COVID-19 Surviving Nurses: A Threat to Medical Systems and Quality of Care

The COVID- 19 pandemic has created many challenges for health care sector around the world. One of these challenges is the increasing need for health care workers, especially nurses. According to the International Nursing Council (ICN) about 6% of COVID-19 cases were among health care workers (range 0 to 18%). Because most nursing activities require direct contact with patients, nurses are more...

متن کامل

The left half of the XMRV retrovirus is present in an endogenous retrovirus of NIH/3T3 Swiss mouse cells.

Xenotropic murine leukemia virus-related virus (XMRV) is a gammaretrovirus found in association with human prostate cancer and chronic fatigue syndrome, although these associations are controversial. XMRV shows at most 94% identity to known mouse retroviruses. Here we used XMRV-specific PCR to search for a more closely related source of XMRV in mice. While we could not find a complete copy, we ...

متن کامل

The Effectiveness of Acceptance and Commitment Therapy on Chronic Fatigue Syndrome and Pain Perception in People With Multiple Sclerosis

Objectives The present study investigated the effectiveness of Acceptance and Commitment Therapy (ACT) on Chronic Fatigue Syndrome (CFS) and Pain Perception (PP) in people with Multiple Sclerosis (MS).  Methods This was a quasi-experimental study with a pre-test, post-test and a control group design. The statistical population was all individuals with MS referring to the MS Society of Ahvaz, I...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Journal of clinical pathology

دوره 45 12  شماره 

صفحات  -

تاریخ انتشار 1992